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NextA Thriller of Genetic Greed, Legal Loopholes, and the Commodification of Human Life

Michael Crichton · 2006

A chilling, fast-paced dive into the legal and ethical wild west of genetic engineering, where your own DNA can be patented, stolen, and sold by corporations.

New York Times BestsellerPrescient Biological ThrillerFinal Crichton Masterpiece Published AliveBioethics Landmark Fiction
7.8
Overall Rating
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20%
Of the Human Genome Patented by 2006
3B
Cost to Sequence First Human Genome in Dollars
1990
Moore v. Regents of the University of California Decision
5
Intersecting Plotlines Showcasing Genetic Abuse

The Argument Mapped

PremiseThe disastrous consequ…EvidenceThe Moore v. Regents…EvidenceThe Suppression of R…EvidenceThe Creation of Tran…EvidenceThe Fraudulence of G…EvidenceThe Conflict of Inte…EvidenceThe Lack of Genetic …EvidenceThe Incompetence of …EvidenceThe Myth of Biologic…Sub-claimPatenting genes viol…Sub-claimConsent is rendered …Sub-claimMedia sensationalism…Sub-claimThe legal system is …Sub-claimTransgenic research …Sub-claimGenetic discriminati…Sub-claimGene therapy is stil…Sub-claimNature will inevitab…ConclusionAn urgent call for the…
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The argument map above shows how the book constructs its central thesis — from premise through evidence and sub-claims to its conclusion.

Before & After: Mindset Shifts

Before Reading Bodily Autonomy

I believe that my body and the cells within it are my absolute, sovereign property. If a doctor removes tissue from me during a procedure, I assume it is simply discarded or destroyed, but it fundamentally remains 'mine'.

After Reading Bodily Autonomy

I now understand that under current legal precedents, once tissue leaves my body, I surrender all ownership and commercial rights to it. Researchers and corporations can legally harvest my unique biology, patent it, and build billion-dollar industries without my knowledge or consent.

Before Reading Intellectual Property

Patents are essential for driving scientific innovation and ensuring that brilliant inventors are rewarded for creating new, life-saving medicines and technologies. Without patents, the medical industry would stagnate and cures would never be found.

After Reading Intellectual Property

Gene patents actually stifle scientific progress by locking foundational biological knowledge behind corporate paywalls, preventing other researchers from developing tests or cures. The current system allows corporations to claim 'invention' over naturally occurring phenomena, creating dangerous monopolies that harm public health.

Before Reading Scientific Objectivity

University scientists and researchers are dedicated solely to the pursuit of truth and the betterment of humanity, operating far above the petty concerns of commercial greed. Academic institutions are bastions of pure, uncorrupted knowledge.

After Reading Scientific Objectivity

Modern academic research is deeply entangled with venture capital, and many scientists are highly motivated by the prospect of lucrative patents and corporate spin-offs. This financial conflict of interest routinely compromises scientific integrity, leading to suppressed data and unethical experimentation.

Before Reading Genetic Privacy

My DNA is a private matter, safely locked away inside my cells, and nobody can access my genetic information without my explicit, written permission and a blood test. I am protected by medical privacy laws.

After Reading Genetic Privacy

I shed my DNA everywhere I go, and it can be easily and legally harvested from a discarded coffee cup or a stray hair. Genetic privacy is largely an illusion, and my biological code is highly vulnerable to being sequenced and analyzed by unauthorized third parties.

Before Reading Human/Animal Boundaries

There is a clear, immutable biological line separating human beings from animals, and our laws and ethics are firmly built upon this unshakeable distinction. A human is a human, and an animal is an animal.

After Reading Human/Animal Boundaries

Transgenic research and the creation of chimeras are rapidly blurring the line between species, creating organisms that possess significant human genetics and near-human traits. The legal and ethical frameworks we rely on are completely unprepared to address the rights of these genetically blended entities.

Before Reading Biological Determinism

If I possess a specific gene for a disease or a trait, it is my absolute destiny, and my future is entirely written in my DNA code. Genetics is a perfect blueprint that dictates exactly who I am and what will happen to me.

After Reading Biological Determinism

Genetics is incredibly complex, influenced by environmental factors and epigenetics; possessing a gene only indicates a probability, not an absolute certainty. The biotech industry wildly exaggerates genetic determinism in order to sell tests and therapies based on fear and oversimplification.

Before Reading Regulatory Protection

Government agencies like the FDA and the patent office are highly competent watchdogs that thoroughly understand the technologies they regulate and rigorously protect the public from harm. They would never allow dangerous or unethical practices.

After Reading Regulatory Protection

Regulatory bodies are chronically underfunded, technologically outpaced, and deeply influenced by the industries they are supposed to oversee. They routinely grant absurd patents and fail to protect the public from the rapid, aggressive overreach of the biotechnology sector.

Before Reading Medical Consent

When I sign a medical consent form, I am simply acknowledging the risks of a surgical procedure, and the hospital is acting entirely in my best medical interest. The forms are just standard legal formalities.

After Reading Medical Consent

Medical consent forms are often predatory legal documents designed to legally strip me of the rights to my own biological material. Hospitals use these broad waivers to ensure they have absolute commercial control over any valuable genetics they discover in my tissue.

Criticism vs. Praise

72% Positive
72%
Praise
28%
Criticism
The New York Times
Major Publication
"Crichton’s narrative is chopped into so many frantic, episodic subplots that t..."
60%
Washington Post
Major Publication
"A terrifyingly plausible and highly entertaining romp through the lawless fronti..."
85%
Scientific American
Scientific Journal
"While Crichton rightly highlights the absurdities of the patent system, his port..."
55%
Entertainment Weekly
Entertainment Magazine
"Fast, fun, and fiercely polemical, Next is Michael Crichton doing what he does b..."
80%
The Guardian
Major Publication
"The book functions better as a manifesto against gene patenting than as a novel,..."
65%
Kirkus Reviews
Trade Publication
"A kaleidoscopic, multi-strand thriller that cleverly weaves together disparate t..."
75%
Nature (Journal)
Scientific Journal
"Despite the dramatic liberties taken, Crichton effectively mainstreams a vital d..."
70%
USA Today
Major Publication
"Next is a high-octane, terrifying look into a future that is already here, fille..."
88%

Existing legal systems are entirely unequipped to regulate the biotechnology sector, allowing corporations to patent the human genome, steal individual biology, and prioritize intellectual property over human rights and public safety.

We must immediately outlaw the patenting of naturally occurring genetic sequences and establish robust laws protecting individual tissue ownership before humanity is entirely corporatized.

Key Concepts

01
Bodily Commodification

The Human Body as Corporate Property

The book explores the horrifying reality that under current law, an individual's biology is viewed as a mineable resource rather than sovereign territory. Once tissue is removed from a patient, hospitals and researchers can legally harvest it, patent the unique genetics, and generate billions in profit without the patient's consent. This concept overturns the fundamental assumption of bodily autonomy, revealing a system designed to strip wealth and rights from the individual to feed the medical-industrial complex. Crichton uses this to show that modern slavery doesn't require chains, just a medical consent form and a patent office.

Your most valuable asset is not your bank account, but the unique genetic code inside your cells, which you currently have zero legal right to protect or profit from once it leaves your body.

02
Innovation Suppression

Patents as Tools of Monopoly, Not Innovation

The conventional wisdom is that patents are necessary to incentivize scientific discovery and the development of new medicines. Crichton systematically dismantles this idea, showing how gene patents are weaponized by corporations to establish monopolies, block rival research, and charge extortionate fees for basic tests. By patenting the foundational code of a disease, a company can effectively hold the cure hostage, preventing other brilliant minds from working on the problem. The concept proves that in the biological sphere, intellectual property laws actively harm the public good.

Gene patents do not protect the inventor; they protect the corporation's ability to legally prevent anyone else from discovering a cure.

03
Regulatory Failure

The Institutional Blindness of Regulators

The narrative constantly highlights the gross incompetence of government agencies tasked with regulating biotechnology, portraying them as underfunded, technologically illiterate, and deeply compromised by industry lobbyists. The patent office is shown granting absurd patents on naturally occurring phenomena simply because bureaucrats do not understand the science. This regulatory vacuum allows biotech companies to operate with terrifying impunity, dictating the rules of the new biological frontier. The concept warns that relying on reactive, slow-moving government bodies to protect us from rapid technological advancement is suicidal.

The agencies designed to protect the public are functioning instead as the legal enforcement arm of the biotech monopolies they are supposed to regulate.

04
Transgenic Ambiguity

The Blurring of Species Lines

By introducing transgenic creatures like talking parrots and intelligent apes, the book forces a confrontation with the complete lack of legal definition regarding what constitutes a 'human'. If an animal is created with 20% human DNA and exhibits human-like consciousness, our current legal and ethical frameworks have absolutely no mechanism to handle its rights or status. This concept exposes the catastrophic moral void at the heart of genetic engineering, where scientists create chimeras simply because they can, without considering the existential implications. It challenges the rigid biological boundaries that society is built upon.

We are rapidly engineering creatures that will demand human rights, and our legal system has no mathematical formula to determine what percentage of a human genome grants a soul.

05
Academic Corruption

The Death of Pure Science

Crichton attacks the romanticized ideal of the noble university researcher, revealing a modern academic landscape fundamentally corrupted by venture capital. Scientists are depicted as aggressive entrepreneurs who falsify data, steal credit, and rush dangerous therapies to market to secure lucrative IPOs. The pursuit of objective truth has been entirely replaced by the pursuit of intellectual property and corporate spin-offs. This concept explains why the public can no longer implicitly trust medical breakthroughs announced by major universities.

When a university researcher discovers a breakthrough, their first call is no longer to a scientific journal, but to their patent attorney and venture capitalist.

06
Genetic Privacy Illusion

The Myth of Biological Anonymity

The book shatters the illusion that our DNA is secure, demonstrating how easily genetic material can be harvested from everyday environments without consent. Because we constantly shed biological material, our most intimate health data, predispositions, and ancestry are entirely exposed to anyone with access to a sequencing lab. This absolute transparency creates a massive vulnerability, allowing corporations, employers, and even bounty hunters to track and profile individuals. The concept warns that in the biotech age, absolute privacy is biologically impossible.

You leave your most secure, unchangeable password—your DNA—on every coffee cup, doorknob, and handshake you experience.

07
False Determinism

The Marketing Lie of Genetic Destiny

Biotech companies heavily market the idea that our genes are our absolute destiny, using this fear to sell expensive tests and therapies. The novel counters this by emphasizing the immense complexity of the genome and the role of epigenetics, showing that possessing a 'bad' gene rarely guarantees a disease. Crichton argues that biological determinism is a scientifically flawed, reductionist philosophy used primarily as a manipulative sales tactic. This concept empowers the reader to reject the fatalistic narratives peddled by direct-to-consumer genetic testing companies.

Corporations sell the terror of genetic destiny, ignoring the fact that environmental factors and complex protein interactions render most single-gene predictions mathematically absurd.

08
Genetic Redlining

The New Biological Caste System

As genetic testing becomes ubiquitous, the book predicts a terrifying future where this data is used to systematically discriminate against individuals. Insurance companies and employers will naturally seek to minimize risk by denying coverage or jobs to people with genetic markers for expensive diseases. This creates an invisible, legally sanctioned caste system based entirely on inherited biology rather than individual merit or action. The concept warns that without extreme legislative intervention, our DNA will be used as a tool of ultimate social oppression.

In the near future, you will not be denied a job because of your race or gender, but because an algorithm determined your genetic code is a liability to the corporate health plan.

09
Consent Subversion

The Weaponization of Medical Forms

The concept explores how the essential ethical doctrine of 'informed consent' has been subverted by hospital legal departments. Dense, impenetrable waivers are used not to inform the patient, but to legally strip them of all commercial rights to their own tissue. The patient, often vulnerable and requiring immediate care, is forced into a coercive contract they cannot possibly understand. This highlights the profound, predatory power imbalance between the individual citizen and the medical-industrial machine.

The paperwork you sign before surgery is not designed to protect your health; it is a legally binding surrender of your biological property rights.

10
Unpredictable Complex Systems

The Hubris of Biological Engineering

A recurring theme in Crichton's work is the fundamental unpredictability of complex systems, applied here to the human genome. The novel demonstrates that when scientists manipulate a single gene, they often trigger a cascade of unforeseen, disastrous consequences elsewhere in the organism. This concept destroys the arrogant industry claim that genetic engineering is a precise, safe science akin to mechanical engineering. It serves as a stark warning that nature's complexity cannot be entirely mastered, and our attempts to do so carry existential risks.

Biology is not a simple machine that can be safely reprogrammed; it is an infinitely complex web where every single alteration carries the risk of catastrophic, systemic failure.

The Book's Architecture

Part 1

The Theft of Frank Burnet

↳ The law fundamentally protects the corporation's right to profit over the individual's right to their own physical body, turning ordinary citizens into walking gold mines.
~45 Mins

The narrative begins by introducing Frank Burnet, a man whose unique, cancer-resistant cells were harvested during a routine procedure without his knowledge. A university researcher discovers the immense commercial value of Burnet's cell line, patents it, and sells it to a biotech corporation for billions. When Burnet discovers the theft and attempts to sue, the courts rule against him, citing the precedent that he abandoned his tissue. The corporation then realizes Burnet's cell line is degrading and hires heavily armed bounty hunters to forcibly acquire fresh DNA from Burnet's daughter and grandson. The chapter establishes the terrifying legal framework that allows corporations to literally hunt human beings for their biology.

Part 2

The Transgenic Parrot

↳ By creating intelligent chimeras, scientists are casually creating new, sentient species without granting them any legal rights or moral consideration.
~40 Mins

We are introduced to Gerard, an African Grey parrot that has been genetically modified using transgenic technology to possess enhanced intelligence and contextual speech. The parrot escapes from the laboratory and is taken in by a well-meaning family who are astounded by its ability to engage in actual conversation and problem-solving. Through Gerard's interactions, Crichton explores the profound ethical implications of engineering human-like consciousness into animals. The scientists who created Gerard view him merely as intellectual property to be recovered or destroyed, completely ignoring the sentience they have engineered. This arc forces the reader to confront the moral void of unregulated bioengineering.

Part 3

The Gene Therapy Scam

↳ The desperate desire for a biological quick-fix allows charlatans to conduct lethal human experimentation under the guise of cutting-edge medicine.
~50 Mins

The book shifts focus to the booming, unregulated industry of gene therapy clinics offering miraculous cures for everything from addiction to aging. A desperate character undergoes an illegal, highly experimental gene therapy using a viral vector, believing it will cure a debilitating condition. The procedure triggers a catastrophic immune response, highlighting the lethal instability of rushing genetic modifications to human trials. Crichton exposes how these clinics prey on the terrified and the vulnerable, using complex scientific jargon to mask fundamentally flawed and dangerous practices. It serves as a stark warning against the utopian promises peddled by biotech marketers.

Part 4

The Bounty Hunter's Pursuit

↳ When intellectual property laws are applied to human biology, they inevitably result in physical violence and the loss of fundamental human rights.
~45 Mins

The narrative follows the ruthless corporate mercenaries hired to extract DNA from Frank Burnet's descendants. They utilize extreme, illegal surveillance tactics, demonstrating the complete lack of genetic and physical privacy in the modern world. They target Burnet's daughter and attempt to surreptitiously harvest her hair and saliva, escalating to physical intimidation and kidnapping. The legal system is shown to be entirely complicit, granting injunctions that essentially legalize this corporate terrorism. This arc transforms the abstract concept of patent law into a visceral, high-stakes physical thriller.

Part 5

The Humanzee's Dilemma

↳ Our entire legal and moral framework relies on a distinct boundary between human and animal that genetic engineering is rapidly erasing.
~40 Mins

Crichton introduces Bouncer, an ape that has been genetically modified with human DNA to the point where it looks, acts, and thinks dangerously close to a human child. Bouncer's creator secretly integrates the ape into his own family, raising him alongside his human children and sending him to school. This creates a deeply uncomfortable exploration of what defines humanity and family when biological lines are intentionally blurred. The inevitable discovery of Bouncer's true nature sparks a legal and media firestorm over whether the creature is a corporate asset or an adopted child. It is the ultimate test of the legal system's inability to handle chimeras.

Part 6

Academic Corruption Exposed

↳ The profit motive has entirely consumed academia, meaning public health decisions are now driven by stock valuations rather than scientific truth.
~35 Mins

The story delves into the laboratories of a major university, where researchers are in a cutthroat race to isolate and patent a profitable gene sequence. The lead scientist is shown manipulating data, hiding adverse reactions, and backstabbing colleagues to ensure he secures venture capital funding. The pure pursuit of scientific knowledge is depicted as completely dead, replaced by the frenzied desire for an Initial Public Offering (IPO). Crichton meticulously details how the influx of corporate money has fundamentally destroyed the objectivity and integrity of academic institutions. This chapter dismantles the myth of the noble, disinterested scientist.

Part 7

The False Positives of Testing

↳ Genetic testing companies sell catastrophic anxiety based on mathematical correlations that are often medically meaningless for the individual.
~45 Mins

A subplot follows a character who takes a direct-to-consumer genetic test and receives a devastating report indicating a high probability of a fatal genetic disease. This triggers a massive emotional and financial crisis as the character drastically alters their life based on this information. It is later revealed that the test was fundamentally flawed, relying on outdated SNPs and ignoring crucial epigenetic factors. Crichton uses this to savage the predictive genetic testing industry, demonstrating how it profits by manufacturing absolute terror out of complex, uncertain probabilities. It is a harsh critique of biological determinism.

Part 8

The Legal Minefield

↳ Justice in the biotech age is determined entirely by which side can afford the largest team of patent attorneys, not by ethics or scientific truth.
~40 Mins

The various legal battles in the book converge, showcasing the absolute dysfunction of the court system when dealing with biotechnology. Patent trolls file frivolous lawsuits that freeze legitimate medical research, and judges make sweeping rulings based on a profound misunderstanding of molecular biology. The sheer cost of litigation ensures that massive corporations always defeat individual citizens or smaller research labs, regardless of ethical merit. Crichton portrays the legal system not as a purveyor of justice, but as a blunt instrument used to enforce corporate monopolies. The chapter proves the law is fatally outpaced by science.

Part 9

The Media Circus

↳ The media's demand for sensationalism actively prevents the public from understanding the very real, very legal dangers of the biotech industry.
~30 Mins

As the existence of the transgenic parrot and the humanzee become public, the media descends, creating a hysterical circus of misinformation. News anchors wildly speculate about 'designer babies' and 'mutant monsters', entirely missing the nuanced legal and ethical issues at the core of the crisis. Crichton uses this chapter to critique the press's role in fueling public ignorance, showing how complex science is reduced to terrifying soundbites for ratings. This manufactured hysteria plays directly into the hands of the biotech corporations, who use the confusion to push through favorable legislation. It highlights the impossibility of having a rational public debate.

Part 10

The Chimera's Fate

↳ When life is defined solely as intellectual property, empathy and morality are legally irrelevant.
~45 Mins

The legal battle over Bouncer the humanzee reaches its climax, forcing the courts to decide if he is a piece of patented property to be destroyed, or a being with rights. The corporation ruthlessly asserts its ownership, treating the intelligent, terrified creature exactly like a malfunctioning piece of machinery. The family's desperate attempt to save Bouncer fails against the ironclad patent laws that explicitly protect the corporation's investment over biological empathy. This tragic conclusion serves as Crichton's ultimate warning about the dehumanizing nature of commodifying life. It is a bleak demonstration of a system without a soul.

Part 11

The Escape and the Aftermath

↳ There is no running away from a threat when the asset they are hunting is written into every cell of your body.
~40 Mins

Frank Burnet's family manages a harrowing escape from the corporate bounty hunters, but they are forced to completely abandon their lives and go into hiding. They realize that as long as their genetic code is patented and valuable, they will never be truly safe or free. The corporations face almost zero legal repercussions for their domestic terrorism, protected by the very laws they lobbied to create. The narrative concludes without a neat resolution, leaving the characters in a state of permanent biological paranoia. It underscores the pervasive, inescapable nature of the threat.

Part 12

Author's Note and Call to Action

↳ The terrifying events of the novel are not speculative fiction; they are the logical, inevitable conclusion of our current, deeply flawed patent laws.
~20 Mins

Crichton breaks from the fictional narrative to deliver a direct, impassioned essay summarizing the real-world facts behind the novel. He explicitly demands the cessation of all gene patenting, arguing it is intellectually bankrupt and a severe threat to human health and scientific progress. He cites real statistics, court cases, and the Myriad Genetics controversy to prove his fictional dystopia is already a legal reality. He outlines specific legislative steps required to protect tissue ownership and ensure open scientific data. This final section transforms the thriller into a serious, actionable political manifesto.

Words Worth Sharing

"The greatest danger we face is not from the science itself, but from the arrogant assumption that we have the wisdom to control it before we even truly understand it."
— Michael Crichton (Author's Note)
"We cannot allow the fundamental building blocks of life to be fenced off and hoarded by corporate interests; our biology is our shared heritage, not a commodity."
— Michael Crichton (Author's Note)
"True innovation requires the free exchange of ideas, not a legal minefield where discovering a natural truth is treated as an infringement of corporate property."
— Michael Crichton (Themes)
"We must demand a legal system that protects the individual from the relentless, terrifying overreach of technologies that strip away our very humanity."
— Michael Crichton (Themes)
"You can’t patent the sun, you can’t patent the wind, and you sure as hell shouldn’t be able to patent the genes that God put inside my body."
— Character Dialogue (Next)
"The law is always fifty years behind the science, and in that gap, corporations are making billions of dollars while rewriting the definition of human life."
— Character Dialogue (Next)
"When you sequence a genome, you aren't inventing a new machine; you are simply translating a book that nature wrote billions of years ago."
— Character Dialogue (Next)
"The danger of transgenic research isn't that the animals will become monsters, but that we will realize how closely related to the monsters we actually are."
— Character Dialogue (Next)
"In the modern age, your most private information isn't your bank account or your search history; it's the biological code you leave behind on every glass you touch."
— Character Dialogue (Next)
"The patent office has become a rubber stamp for biotech companies, granting monopolies over natural elements because bureaucrats simply do not understand the science they are regulating."
— Michael Crichton (Author's Note)
"Universities used to be sanctuaries for objective truth; now they are little more than taxpayer-funded incubators for private venture capital firms."
— Character Dialogue (Next)
"We are creating a new biological underclass, where people will be denied insurance and employment not for what they have done, but for what their DNA suggests they might do."
— Character Dialogue (Next)
"The media's desperate need for sensational headlines has turned complex genetic science into a carnival of false hopes and terrifying, unscientific fear-mongering."
— Character Dialogue (Next)
"By the early 2000s, nearly one-fifth of the human genome had already been patented by private corporations and universities."
— Author's Note (Next)
"The Moore v. Regents case established the horrific precedent that patients have no property rights to the cells removed from their own bodies."
— Legal Context (Next)
"The cost of developing a single viable gene therapy often exceeds hundreds of millions of dollars, driving the desperate need for broad, restrictive patents."
— Industry Context (Next)
"A single human cell contains roughly three billion base pairs of DNA, a complexity that renders the idea of simplistic 'designer babies' mathematically absurd."
— Scientific Context (Next)

Actionable Takeaways

01

Your Body is Not Legally Yours

The most shocking revelation of the book is that under existing case law, you do not own the cells, tissues, or genetic material removed from your body. Once discarded, it becomes the property of whoever collects it, allowing corporations to harvest and monetize your unique biology without your consent. You must aggressively protect your bodily autonomy by scrutinizing medical consent forms.

02

Gene Patents Destroy Innovation

The biotech industry claims patents are necessary for research, but Crichton proves they actually suppress it by creating monopolies over natural phenomena. When a company patents a gene, they legally block other scientists from studying it or developing alternative cures, effectively holding medical progress hostage. We must advocate for open-source biology to accelerate true medical breakthroughs.

03

Genetic Privacy is a Myth

Because you constantly shed DNA into your environment, your most intimate biological information is entirely vulnerable to covert collection and sequencing. The idea that your genetic code is private is a dangerous illusion in an era of cheap, rapid DNA testing. You must operate under the assumption that your genetic vulnerabilities are accessible to determined third parties.

04

Beware Biological Determinism

Direct-to-consumer genetic testing companies sell the lie that your genes are your absolute destiny in order to manufacture fear and drive sales. In reality, human biology is infinitely complex, and possessing a specific gene is only a probability, heavily influenced by environment and epigenetics. Do not make drastic life decisions based on the oversimplified results of a commercial DNA kit.

05

The Corporatization of Academia

University research departments are no longer bastions of objective truth; they are deeply entangled with venture capital and driven by the pursuit of lucrative patents. This conflict of interest fundamentally compromises scientific integrity, leading to suppressed data and dangerous, rushed therapies. You must always question the financial backing behind any new 'miraculous' medical study.

06

Regulatory Agencies are Outpaced

Institutions like the FDA and the patent office are hopelessly behind the curve of rapid biotechnological advancement, granting absurd patents and failing to protect the public. We cannot rely on these slow, reactive bodies to govern technologies that can irrevocably alter the human genome. Citizens must demand proactive, highly informed bio-legislation.

07

The Threat of Transgenic Ethics

Scientists are actively blurring the lines between species by creating chimeras, yet we have no legal or moral framework to determine the rights of these organisms. This unregulated engineering forces us to ask terrifying questions about what constitutes a human being. We must establish international boundaries on transgenic research before a crisis occurs.

08

Consent Forms are Predatory

Standard medical consent forms are often weaponized by hospital legal teams to ensure the patient waives all commercial rights to their own tissue. These dense, impenetrable documents are designed to protect corporate monopolies, not patient health. Always attempt to read, understand, and negotiate the terms of your medical waivers.

09

Genetic Discrimination is Coming

As genetic testing becomes standard, institutions will use this data to deny employment, insurance, and loans to those with 'undesirable' genetic markers. This will create a new, invisible biological caste system where individuals are mathematically penalized for inherited traits. We need immediate, airtight legislation to prevent this high-tech redlining.

10

Biology Cannot Be Mastered

The overarching theme of Crichton's work is the supreme arrogance of believing we can perfectly control complex systems like the human genome. Modifying a single gene often triggers unpredictable, catastrophic cascades elsewhere in the organism. We must approach genetic engineering with extreme humility rather than corporate hubris.

30 / 60 / 90-Day Action Plan

30
Day Sprint
60
Day Build
90
Day Transform
01
Audit Medical Consents
Before your next medical procedure or blood draw, explicitly ask to read the fine print regarding tissue retention and research. Request to cross out or modify clauses that grant the institution indefinite commercial rights to your biological material. This immediate action challenges the default assumption of the medical system and forces a conversation about your bodily autonomy. Monitor if the clinic is willing to negotiate or if they use coercion to force you to sign standard waivers.
02
Research Direct-to-Consumer DNA Tests
Investigate the deeply buried privacy policies of popular genetic testing companies like 23andMe or AncestryDNA before submitting any samples. Understand precisely who they are legally allowed to sell your genetic data to, including pharmaceutical companies and law enforcement agencies. This action prevents you from unwittingly entering your most intimate biological code into a monetized corporate database. Seek out services that guarantee absolute data destruction after analysis.
03
Educate on Gene Patent Laws
Spend time researching the current legal status of gene patenting in your country, specifically the aftermath of the 2013 Supreme Court ruling (Association for Molecular Pathology v. Myriad Genetics). Understand the difference between patenting naturally occurring DNA and patenting synthetic cDNA. This foundational knowledge is critical for understanding the ongoing battles over intellectual property in the biotech sector. Use this knowledge to critically evaluate news about 'breakthrough' genetic cures.
04
Secure Genetic Data
If you have already used a commercial DNA testing service, immediately log into your account and navigate to the privacy settings. Opt out of all third-party research sharing and request the physical destruction of your biological sample. This action limits the ongoing exposure of your genetic profile to secondary markets and data breaches. Verify via email confirmation that your sample has actually been destroyed, not just anonymized.
05
Analyze Media Framing
For the next month, critically analyze how mainstream media reports on genetic discoveries, looking for sensationalism and oversimplification. Identify instances where complex genetic probabilities are falsely reported as absolute biological destinies or 'miracle cures'. This practice inoculates you against the manipulative hype generated by biotech PR departments. You will begin to see how public ignorance is systematically manufactured to support corporate valuations.
01
Advocate for Legislative Action
Draft letters to your local and national representatives demanding robust, updated legislation that explicitly protects genetic privacy from employers and insurance companies. Reference specific loopholes in existing laws like GINA (Genetic Information Nondiscrimination Act) that leave certain types of insurance unprotected. This transitions your awareness from personal protection to civic action, pushing back against corporate lobbying. Track the voting records of these representatives on biotech regulation.
02
Discuss Genetic Privacy with Family
Initiate a serious conversation with your immediate family about the implications of commercial DNA testing, explaining that one person's test exposes the genetic markers of their relatives. Establish a family consensus on whether to participate in these databases, respecting the privacy boundaries of the group. This action recognizes that DNA is a shared asset and prevents one family member from inadvertently compromising the genetic privacy of siblings or children. Ensure everyone understands the long-term consequences of these databases.
03
Investigate Academic Funding
When reading about a new medical breakthrough from a university, actively trace the funding sources and the researchers' corporate affiliations. Look for conflicts of interest where the lead scientist also sits on the board of the venture capital firm funding the spin-off company. This action demystifies the illusion of pure academic research and helps you evaluate the true motivations behind scientific claims. You will develop a highly critical eye for compromised scientific literature.
04
Support Open-Source Biology
Identify and financially support organizations and research initiatives that are committed to open-source genetics and refuse to patent foundational biological discoveries. These groups operate in direct opposition to the monopolistic practices criticized in the book. By directing resources to open science, you help build an alternative ecosystem that prioritizes human health over corporate profit. Follow their publications to see how unencumbered research progresses faster.
05
Explore Epigenetics
Read scientifically robust introductory materials on epigenetics to understand how lifestyle, environment, and stress alter gene expression without changing the DNA sequence itself. This shatters the fatalistic mindset of biological determinism promoted by the testing industry. This action empowers you by demonstrating that your lifestyle choices actively influence how your genetic code manifests. Apply this knowledge to your daily health routines.
01
Establish a Medical Directive
Work with a lawyer to draft a highly specific advance medical directive that explicitly prohibits the commercial harvesting, patenting, or sale of any tissue removed from your body during life or after death. Ensure this document is attached to all your medical records at your primary care physician and local hospitals. This creates a legally binding barrier against the covert theft of your biological material. Review and update this document annually to keep pace with changing case law.
02
Audit Biotech Investments
If you hold mutual funds or individual stocks, audit your portfolio to identify investments in biotechnology companies heavily reliant on gene patenting or aggressive litigation against researchers. Consider divesting from companies whose business models are fundamentally misaligned with ethical bio-practices. This action aligns your financial resources with your ethical understanding of tissue ownership and open science. Reallocate those funds to companies focused on ethical diagnostics or open-source medical tools.
03
Monitor Transgenic Legislation
Set up news alerts to track international legislation regarding transgenic research, chimeras, and the biological definitions of humanity. Stay informed on where the scientific community is pushing ethical boundaries, such as growing human organs in pigs. This high-level vigilance ensures you are not blindsided by radical shifts in biotechnology that could fundamentally alter human society. Use this information to participate in informed public debates on bioethics.
04
Challenge Institutional Mandates
If an employer or insurance provider attempts to mandate any form of genetic testing or requests access to your genetic history, formally refuse and cite applicable privacy laws. Be prepared to seek legal counsel if they attempt to penalize you for protecting your biological data. This aggressive action is necessary to halt the creeping normalization of corporate genetic surveillance. Document all interactions meticulously to build a case if discrimination occurs.
05
Host a Bioethics Forum
Organize a book club or community discussion group focused on 'Next' and similar texts to educate your local network about the realities of the biotech industry. Facilitate debates on tissue ownership, gene patents, and the illusion of genetic privacy. This action multiplies the book's impact, transforming passive readers into an informed, critical public. An educated populace is the only effective defense against the predatory practices of the medical-industrial complex.

Key Statistics & Data Points

20% Patented

By the time the novel was published, it was estimated that roughly one-fifth of the entire human genome had been patented by private corporations, universities, and research institutes. This statistic proves that the commodification of human life is not a future dystopia, but an ongoing, aggressive reality. It highlights the massive scale of the legal land-grab occurring within our own biology, a fact most citizens remain completely unaware of.

Source: Scientific Consensus / Author's Note (2006)
Moore v. Regents (1990)

The landmark California Supreme Court case ruled that John Moore had no property rights to his discarded spleen cells, which researchers had secretly used to create a cell line valued at an estimated $3 billion. This legal precedent forms the terrifying backbone of Crichton's narrative, legally validating the theft of individual biology. It demonstrates how the justice system fundamentally privileges corporate research over individual bodily autonomy.

Source: California Supreme Court (1990)
3 Billion Base Pairs

The human genome consists of approximately three billion base pairs of DNA, creating a system of incomprehensible complexity and interdependence. Crichton uses this statistic to mock the hubris of scientists and corporations who claim they can perfectly control or predict genetic outcomes by tweaking a single gene. It underscores the profound danger of tampering with a system that is vastly more complicated than our current models suggest.

Source: Human Genome Project Data
100,000 to 20,000 Genes

Initial estimates assumed humans had over 100,000 genes to account for our complexity, but the Human Genome Project revealed we have only about 20,000—roughly the same as a roundworm. This massive failure in scientific prediction is highlighted in the book to show that genetics is not a simple, linear blueprint. It forces a paradigm shift towards understanding epigenetics and protein interactions, destroying the simplistic marketing narratives of the biotech industry.

Source: Human Genome Project Results
Hundreds of Millions in R&D

The pharmaceutical and biotech industries frequently cite that bringing a new gene therapy or drug to market costs hundreds of millions, if not billions, of dollars. The book explores how this massive financial burden is used to justify the aggressive pursuit of broad, restrictive patents. It exposes the harsh economic reality that profit, not altruism, dictates the direction and availability of modern medical research.

Source: Biotechnology Industry Averages
BRCA1 and BRCA2 Patents

While heavily implied in the text and author's note, the real-world patents held by Myriad Genetics on the BRCA1 and BRCA2 breast cancer genes serve as the ultimate example of the book's thesis. Because one company held the patent, they could charge exorbitant fees for the test and prevent other scientists from developing alternative screening methods. This specific instance proves Crichton's core argument that gene patents actively harm patients and suppress critical medical research.

Source: Myriad Genetics Controversy
Dozens of Transgenic Species

The novel highlights the very real, ongoing creation of dozens of transgenic animal species in laboratories worldwide, from glow-in-the-dark pigs to mice with human brain cells. This statistic shatters the illusion that genetic engineering is purely theoretical, showing it is a widespread, unregulated industry practice. It forces the reader to confront the ethical nightmare of inter-species chimera research that is happening right now, completely out of the public eye.

Source: General Bioengineering Data
Hepatitis C Viral Vector Failure

The narrative references real-world tragedies where early gene therapy trials utilized viral vectors that caused catastrophic immune responses, leading to patient deaths or leukemia. This data point is crucial for dismantling the utopian promises of gene therapy, revealing it as a highly volatile, experimental procedure. It underscores the reckless speed at which companies rush dangerous technologies to human trials in pursuit of patent dominance.

Source: Early Gene Therapy Clinical Trials

Controversy & Debate

The Viability and Ethics of Gene Patenting

Crichton's primary crusade in 'Next' is against the practice of patenting natural genetic sequences, arguing it stifles research and constitutes theft of the human heritage. The biotechnology industry vehemently opposed this view, arguing that without the financial protection of patents, no company would invest the billions required to develop genetic therapies. Critics accused Crichton of wildly misunderstanding patent law, noting that patents apply to isolated DNA, not DNA residing in the body. Despite the pushback, Crichton's stance was largely vindicated in 2013 when the Supreme Court ruled that naturally occurring DNA segments cannot be patented.

Critics
Biotechnology Innovation Organization (BIO)Myriad GeneticsVarious Patent Attorneys
Defenders
Michael CrichtonAmerican Civil Liberties Union (ACLU)Association for Molecular Pathology

Portrayal of the Scientific Community

The novel paints a scathingly bleak picture of modern academia, portraying scientists as arrogant, greedy, and thoroughly corrupted by venture capital and the pursuit of patents. The scientific community reacted with intense frustration, arguing that Crichton was unfairly demonizing an entire profession and ignoring the millions of researchers dedicated to ethical, life-saving work. They claimed his sensationalized portrayal would erode public trust in vital medical research. Defenders of the book noted that Crichton was satirizing a very real systemic issue regarding the corporatization of universities.

Critics
Scientific AmericanNature MagazineVarious Academic Researchers
Defenders
Bioethics WatchdogsCritics of Corporate AcademiaMichael Crichton

The Transgenic Ape and the Parrot

To illustrate the absurdity of unregulated genetics, Crichton introduces a parrot capable of advanced, contextual speech and a transgenic ape (Bouncer) that is legally adopted and attends school. Critics found these plotlines absurdly far-fetched and cartoonish, arguing they detracted from the serious legal arguments regarding tissue ownership and patents. They felt these elements pushed the book too far into pulp science fiction, undermining its credibility. Defenders argued these chimeras were necessary satirical tools to force readers to confront the extreme ethical boundaries of what constitutes 'humanity'.

Critics
The New York Times Book ReviewMainstream Literary CriticsPrimatologists
Defenders
Science Fiction FansSatiristsAnimal Rights Ethicists

Structural Fragmentation of the Narrative

Unlike his previous, tightly focused thrillers like 'Jurassic Park', 'Next' features dozens of loosely connected subplots, news clippings, and sudden character shifts that bounce rapidly across the country. Literary critics widely panned this structure as disjointed, chaotic, and frustrating to read, claiming Crichton sacrificed narrative cohesion to cram in as many bio-anecdotes as possible. The sheer volume of characters made it difficult to emotionally invest in any single storyline. Defenders countered that the chaotic structure perfectly mirrored the fragmented, lawless, and confusing landscape of the modern biotechnology industry.

Critics
Washington Post Fiction ReviewersKirkus ReviewsTraditional Thriller Fans
Defenders
Postmodern Fiction AdvocatesBioethics ScholarsCrichton Loyalists

The Personal Attack on Michael Crowley

In a highly controversial move, Crichton included a minor character in the book named 'Mick Crowley'—a Washington political columnist depicted as a pedophile with a small penis. This was widely recognized as a direct, vicious retaliation against real-life journalist Michael Crowley, who had previously written an unflattering review of Crichton's novel 'State of Fear'. The literary world condemned this inclusion as incredibly petty, unprofessional, and an abuse of an author's platform. This bizarre feud overshadowed much of the book's actual scientific message during its initial press tour.

Critics
Michael CrowleyThe New RepublicMainstream Journalism Outlets
Defenders
Free Speech AbsolutistsHardcore Crichton Fans (A minority)

Key Vocabulary

Gene Patent Transgenic Cell Line Moore v. Regents Chimera Bioethics Gene Therapy Bounty Hunter Epigenetics Telomerase Recombinant DNA Informed Consent Venture Capital SNP (Single Nucleotide Polymorphism) Genetic Discrimination Patent Troll Viral Vector Commodity

How It Compares

Book Depth Readability Actionability Originality Verdict
Next
← This Book
8/10
9/10
5/10
8/10
The benchmark
Jurassic Park
Michael Crichton
8/10
10/10
2/10
10/10
Jurassic Park focuses on the macro-dangers of cloning and chaos theory, providing a more focused and iconic narrative. Next tackles the micro-dangers of modern genetics and legal loopholes, offering a more fragmented but arguably more realistic and immediate critique.
The Immortal Life of Henrietta Lacks
Rebecca Skloot
10/10
9/10
7/10
9/10
Skloot's book is a masterful work of non-fiction that explores the real-world tragedy of stolen cell lines, serving as the historical grounding for Crichton's fiction. Next fictionalizes and extrapolates these issues into a thriller format, making the concepts highly accessible but less emotionally resonant than the true story of HeLa.
Altered Carbon
Richard K. Morgan
7/10
8/10
1/10
9/10
Altered Carbon imagines a far-future where human consciousness can be downloaded, exploring the ultimate commodification of the human body. Next grounds its exploration of bodily commodification in the very immediate, near-term reality of gene patenting and corporate biology.
Gattaca (Screenplay/Film context)
Andrew Niccol
8/10
8/10
3/10
9/10
Gattaca explores the social consequences of genetic discrimination and the creation of a biological caste system. Next similarly warns against genetic redlining, but focuses far more on the legal and corporate mechanics that would enable such a dystopian society to function.
Brave New World
Aldous Huxley
9/10
7/10
2/10
10/10
Huxley's classic warns of a state-controlled biological dystopia where citizens are engineered for servitude. Crichton’s Next warns of a corporately-controlled biological dystopia where citizens are engineered and mined purely for intellectual property and profit.
Prey
Michael Crichton
7/10
9/10
2/10
8/10
Prey deals with the unchecked, catastrophic consequences of nanotechnology and swarm intelligence escaping the lab. Next applies that exact same cautionary template to transgenic research and gene therapy, arguing that biology is just as unpredictable as nanotech.

Nuance & Pushback

Cartoonish Villainy of Scientists

Critics argue that Crichton demonizes the entire scientific community, portraying geneticists as uniformly greedy, amoral, and incompetent. This broad-brush characterization ignores the thousands of researchers dedicated to ethical, life-saving work, reducing complex systemic issues to the actions of mustache-twirling villains. Defenders note that Crichton is satirizing the very real corrupting influence of venture capital, but the extreme portrayal often undermines the book's credibility.

Chaotic, Fragmented Narrative Structure

The novel jumps erratically between dozens of loosely connected subplots, news clippings, and minor characters, severely hindering narrative momentum. Many reviewers found this structure incredibly frustrating, claiming it felt more like an angry collection of op-eds than a cohesive thriller. While defenders argue it mirrors the chaotic nature of the biotech industry, it undeniably sacrifices the tight, relentless pacing Crichton was famous for.

Overly Sensationalized Chimeras

The inclusion of a talking, French-speaking parrot and an ape that attends public school pushed the narrative too far into pulp science fiction for many serious readers. Critics felt these absurd elements detracted from the very grounded, terrifying legal arguments about patent law and tissue ownership. They argued these cartoonish chimeras diluted the book's vital message, though some defended them as necessary philosophical thought experiments.

Petty Retaliation Against a Journalist

The inclusion of the character 'Mick Crowley'—a thinly veiled, malicious attack on real-life critic Michael Crowley—was widely condemned as petty and highly unprofessional. This bizarre, vindictive subplot added nothing to the thematic weight of the novel and distracted heavily from the book's launch and core arguments. It was seen as an abuse of an author's platform to settle a personal score.

Misrepresentation of Patent Law Nuance

Legal scholars criticized Crichton for intentionally simplifying and misrepresenting the nuances of gene patenting to serve his narrative agenda. They pointed out that patents are granted for isolated and purified DNA sequences, not the DNA as it naturally exists inside the human body. While Crichton opposed the entire concept philosophically, critics argued his technical misrepresentations weakened his overall argument for reform.

Heavy-Handed Exposition

Characters frequently halt the plot entirely to deliver long, dry lectures on molecular biology, patent law, and court precedents. This clunky, exposition-heavy dialogue feels highly unnatural and forces the reader to endure massive info-dumps. Critics noted that Crichton struggled to weave his extensive research organically into the story, resulting in a book that often feels like a thinly disguised textbook.

Who Wrote This?

M

Michael Crichton

Master of the Cautionary Techno-Thriller

Michael Crichton was an American author, screenwriter, and film director, universally recognized as the pioneer of the modern techno-thriller genre. He trained as a medical doctor at Harvard Medical School, a background that provided him with a deep, authoritative understanding of complex scientific and biological systems. Crichton famously walked away from medicine to pursue writing, using his rigorous scientific knowledge to craft wildly successful cautionary tales about humanity's hubris, including 'Jurassic Park', 'The Andromeda Strain', and 'Westworld'. Throughout his career, he frequently clashed with the scientific establishment, warning against the dangers of unregulated technology, complex systems theory, and the corrupting influence of corporate money on pure science. 'Next' was his final novel published before his death in 2008, serving as a passionate, culminating manifesto on the bioethical issues that haunted his entire body of work.

M.D. from Harvard Medical SchoolPioneer of the Techno-Thriller Literary GenreCreator of the hit medical drama 'ER'Author of massive global bestsellers including 'Jurassic Park' and 'Sphere'Prominent public critic of the politicization and corporatization of science

FAQ

Is it actually true that corporations can patent human genes?

At the time the book was written (2006), it was entirely true, and roughly 20% of the human genome had been patented. However, in 2013, the Supreme Court ruled in 'Association for Molecular Pathology v. Myriad Genetics' that naturally occurring DNA segments cannot be patented, largely vindicating Crichton's core argument. However, synthetic DNA (cDNA) created in a lab can still be patented, meaning the legal battles over genetic intellectual property are far from over. Crichton's warning remains vital for understanding how corporations attempt to monopolize biology.

Did a hospital really steal a man's cells and make billions?

Yes, Crichton heavily bases the Frank Burnet storyline on the real-world 1990 legal case of John Moore vs. the Regents of the University of California. Doctors removed Moore's cancerous spleen and, without his knowledge, used his unique cells to create a highly lucrative cell line. The California Supreme Court ruled that Moore had no property rights to his discarded tissue, establishing the terrifying legal precedent that Crichton attacks throughout the novel.

Are the transgenic animals in the book based on real science?

While Crichton exaggerates for dramatic effect—there are no talking parrots quoting philosophy or apes attending public school—the underlying science of transgenic chimera research is entirely real. Scientists have successfully created pigs with human blood, mice with human brain cells, and countless other cross-species organisms in laboratories. Crichton takes these existing experiments to their logical, terrifying conclusions to force a necessary debate about bioethics and the legal definition of humanity.

Why did Crichton include a pedophile character named Mick Crowley?

This was a highly controversial act of personal retaliation by Crichton against real-life journalist Michael Crowley, who had previously written a scathing review of Crichton's book 'State of Fear'. Crichton used his massive platform to insert a minor, deeply offensive character with the exact same name as a form of petty revenge. It is widely considered a stain on the novel and a massive distraction from the important scientific arguments the book attempts to make.

Is the book anti-science?

No, Crichton was a medical doctor who was deeply passionate about pure scientific inquiry and discovery. The book is explicitly anti-corporatization; it attacks the way venture capital and patent law have corrupted the scientific method and compromised academic integrity. Crichton argues that true science requires open data and the free exchange of ideas, both of which are destroyed by the biotech industry's obsession with intellectual property monopolies.

How accurate is the portrayal of the legal system?

The book's portrayal of patent trolls, overwhelming corporate litigation, and the utter incompetence of judges dealing with complex science is considered highly accurate by many critics of the patent system. Crichton effectively shows how the sheer cost of legal defense allows massive corporations to steamroll smaller researchers or individual citizens, regardless of who is actually right. The justice system is accurately depicted as a tool used to enforce wealth rather than protect fundamental bio-rights.

Do I really need to worry about genetic privacy?

Yes, the book's warning about genetic privacy is more relevant today than ever before. With the explosion of direct-to-consumer DNA testing like 23andMe, millions of people have willingly handed over their genetic data to corporate databases, which are frequently shared with third parties or law enforcement. Crichton accurately predicted that our genetic code would become the ultimate, highly vulnerable commodity in the information age.

Does the book offer a solution to these problems?

Within the fictional narrative, the characters are largely crushed by the system, offering a bleak, dystopian conclusion. However, Crichton included an explicit 'Author's Note' at the end of the book where he outlines clear, actionable solutions. He calls for an immediate end to gene patenting, the establishment of clear laws regarding tissue ownership, and strict regulations to separate academic research from corporate venture capital.

Why does the narrative jump around so much?

Crichton chose a highly fragmented, multi-strand narrative structure to reflect the chaotic, fast-paced, and wildly unregulated nature of the biotechnology industry itself. By rapidly jumping between bounty hunters, researchers, victims, and transgenic animals, he attempts to show how these issues permeate every level of society simultaneously. While many readers found it frustrating, it was a deliberate stylistic choice to overwhelm the reader with the sheer scale of the genetic crisis.

Is 'Next' as good as 'Jurassic Park'?

Most critics and readers agree that 'Next' lacks the tight, focused narrative momentum and iconic suspense of 'Jurassic Park'. It is far more episodic, fragmented, and exposition-heavy, functioning more as a political manifesto than a streamlined thriller. However, many argue that the specific, real-world issues 'Next' tackles—like tissue ownership and patent law—make it a much more immediate and terrifying book than his dinosaur epic.

Next is a profoundly flawed but urgently necessary piece of fiction that successfully weaponizes the thriller genre to expose the legal and ethical nightmares of the biotechnology industry. While its narrative structure is chaotic and its characters often serve as mere mouthpieces for Crichton's outrage, the core arguments regarding tissue ownership, gene patenting, and academic corruption remain terrifyingly relevant. Crichton correctly diagnosed that the greatest threat to humanity is not rogue science, but the unchecked corporate commodification of life itself within a vacuum of legal regulation. It serves as a vital, highly accessible entry point into the complex world of bioethics, demanding that citizens wake up to the theft of their own biology.

A chilling reminder that in the twenty-first century, your most fundamental human rights end exactly where a corporation's intellectual property begins.